pakd4 - Inferring the Evolutionary History of IncP-1 Plasmids Despite ... sgcwin77

Genetic map of pAKD4. Coding regions are illustrated by ... - ResearchGate

The recombination appears to have been between the ancestor of the IncP-1α plasmids and an IncP-1δ plasmid similar to pAKD4. Visual inspection of the aligned trbB genes also clearly showed a recombination event that included pAKD4, several of the IncP-1β plasmids, and the ancestor of the IncP-1ε plasmids, which would help explain the highly ...

Inferring the Evolutionary History of IncP-1 Plasmids Despite ...

Phylogenetic analysis of plasmid pAKD4— To confirm that pAKD4 is an IncP-1 δ plasmid, a maximum likelihood tree was inferred from concatenated sequences of 20 backbone proteins shared by all ...

PAK4 signaling in health and disease: defining the PAK4-CREB axis

Sen, D. et al. Comparative genomics of pAKD4, the prototype IncP-1delta plasmid with a complete backbone. Plasmid 63, 98-107 (2010).

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Targeting PAK4 to reprogram the vascular microenvironment and ... - Nature

Plasmid pAKD4 was previously isolated by exogenous plasmid isolation from an agricultural soil in Norway. Its 56,803. bp nucleotide sequence shows high similarity in gene sequence and gene order to both plasmids pEST4011 and pIJB1, the only other IncP-1δ plasmids sequenced so far.

Phylogenetic tree showing the relationship of the 12 pAKD plasmids ...

Fig. 3. Phylogenetic tree showing the relationship of pAKD4 with other IncP-1 plasmids. Maximum Likelihood tree was inferred from concatenated amino acid sequences of 20 backbone proteins shared by completely sequenced IncP-1 plasmids and pAKD4. The scale bar represents the probability of amino acid substitutions per site.